Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 9/20 | 0.54 |
| ▸ | HTR1A | P08908 | 7/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 10/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | DRD1 | P21728 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258263 | 0.80 | KMT2A (0.52) | DRD2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL7263869 | 0.79 | ALDH1A1 (0.46) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL7258434 | 0.77 | GFER (0.54) | DRD2DRD3KMT2AMEN1DRD4 | |
| SCHEMBL22113447 | 0.77 | HTR2B (0.78) | HTR2BHTR1ADRD2KMT2AMEN1 | |
| SCHEMBL2626009 | 0.76 | HTR2B (0.44) | HTR2BHTR1ACA2CA9DRD2 | |
| SCHEMBL7262647 | 0.75 | LMNA (0.56) | CA2CA9NPC1RAB9AKMT2A | |
| SCHEMBL7262362 | 0.74 | DRD4 (0.64) | DRD2DRD3DRD1NPC1RAB9A | |
| SCHEMBL7258467 | 0.73 | KMT2A (0.50) | CA2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7258839 | 0.73 | ALDH1A1 (0.62) | DRD2DRD4KDM4EALDH1A1LMNA | |
| SCHEMBL7262997 | 0.73 | ALDH1A1 (0.51) | KMT2AMEN1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082263-A1 | SULFAMIC ACIDS AS INHIBITORS OF HUMAN CYTOPLASMIC PROTEIN TYROSINE PHOSPHATASES | ONTOGEN CORPORATION (US) | 2003-10-09 | — | — | WO | disclosed |