SCHEMBL7258285

SCHEMBL7258285

O=C(CCl)c1snc(Cl)c1Cl

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 13/20 0.37
TRPA1 O75762 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPK1 P28482 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7253463 0.82 GSK3B (0.37) GSK3BALDH1A1
Methylene Chloride SCHEMBL7089348 0.79
SCHEMBL7256271 0.77
SCHEMBL1720501 0.76
SCHEMBL28069297 0.74 ALDH1A1 (0.36) ALDH1A1MAPK1
Hydrochloric Acid SCHEMBL6230305 0.74 ALDH1A1 (0.36) ALDH1A1MAPK1
SCHEMBL28048586 0.74
SCHEMBL7088318 0.74
SCHEMBL7253131 0.74 ADORA2A (0.35)
SCHEMBL7085349 0.73 OGG1 (0.41) ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003031420-A1 ISOTHIAZOLE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2003-04-17 WO disclosed