SCHEMBL725836

SCHEMBL725836

O=C1OCc2ccccc2COC(=O)c2ccc1cc2

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.60
MAOB P27338 1/20 0.60
ALDH1A1 P00352 4/20 0.45
KDM4E B2RXH2 2/20 0.45
CYP1A2 P05177 2/20 0.45
TYMS P04818 1/20 0.45
HPGD P15428 1/20 0.45
CYP2C19 P33261 1/20 0.45
HSD17B10 Q99714 1/20 0.45
KMT2A Q03164 2/20 0.45
PRF1 P14222 2/20 0.44
PTGS1 P23219 3/20 0.41
MAPT P10636 3/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
MEN1 O00255 1/20 0.40
POLB P06746 1/20 0.40
HSD17B3 P37058 1/20 0.38
GSK3B P49841 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29742032 1.00 MAOA (0.60) MAOAMAOBALDH1A1KDM4ECYP1A2
SCHEMBL28603304 0.87 MAOA (0.68) MAOAMAOBALDH1A1KDM4ECYP1A2
SCHEMBL11205483 0.79 MAOA (0.58) MAOAMAOBALDH1A1KDM4ECYP1A2
SCHEMBL28586713 0.77 KMT2A (0.41) MAOAMAOBALDH1A1KDM4ECYP1A2
SCHEMBL6903786 0.75 MAOA (1.00) MAOAMAOBALDH1A1KDM4ECYP1A2
SCHEMBL22284 0.75 MAOA (1.00) MAOAMAOBALDH1A1KDM4ECYP1A2
SCHEMBL11522370 0.75 MAOA (1.00) MAOAMAOBALDH1A1KDM4ECYP1A2
SCHEMBL29448271 0.75 MAOA (1.00) MAOAMAOBALDH1A1KDM4ECYP1A2
SCHEMBL6353583 0.75 MAOA (1.00) MAOAMAOBALDH1A1KDM4ECYP1A2
Hydrochloric Acid SCHEMBL27317247 0.75 KMT2A (0.40) MAOAMAOBALDH1A1KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7935737-B2 Articles derived from compositions containing modified polybutylene terephthalate (PBT) random copolymers derived from polyethylene terephthalate (PET) SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-05-03 US claimed
EP-2635635-B1 FLAME-RESISTANT POLYESTER-POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-09-18 EP disclosed
EP-2370492-B1 POLY(BUTYLENE TEREPHTHALATE) COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-10-17 EP disclosed
EP-2785793-B1 POLYESTER COMPOSITIONS AND INSERT-MOLDED ARTICLES MADE THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-07-18 EP disclosed
EP-2370518-B1 POLY(BUTYLENE TEREPHTHALATE) COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-06-20 EP disclosed
EP-2663592-B1 POLYMER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2016-06-15 EP disclosed
EP-2663593-B1 POLYMER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2016-06-15 EP disclosed
EP-2785793-A1 POLYESTER COMPOSITIONS AND INSERT-MOLDED ARTICLES MADE THEREFROM SABIC Innovative Plastics IP B.V. (NL) 2014-10-08 EP disclosed
US-8853304-B2 Polyester compositions and insert-molded articles made therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-10-07 US disclosed
US-20130317150-A1 FLAME-RESISTANT POLYESTER-POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2013-11-28 US disclosed
US-8138244-B2 Reinforced polyester compositions, method of manufacture, and articles thereof SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-03-20 US disclosed
WO-2012003180-A1 FLAME RESISTANT POLYESTER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES THEREOF SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-01-05 WO disclosed
US-20110319534-A1 FLAME RESISTANT POLYESTER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES THEREOF SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-12-29 US disclosed
EP-2370518-A1 POLY(BUTYLENE TEREPHTHALATE) COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC Innovative Plastics IP B.V. (NL) 2011-10-05 EP disclosed
EP-2370517-A1 REINFORCED POLYESTER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES THEREOF SABIC Innovative Plastics IP B.V. (NL) 2011-10-05 EP disclosed
WO-2010078140-A1 REINFORCED POLYESTER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES THEREOF SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-07-08 WO disclosed
WO-2010078124-A1 POLY(BUTYLENE TEREPHTHALATE) COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-07-08 WO disclosed
US-20100168290-A1 REINFORCED POLYESTER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES THEREOF SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2010-07-01 US disclosed
US-20100168321-A1 POLY(BUTYLENE TEREPHTHALATE) COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-07-01 US disclosed
US-20100168317-A1 POLY(BUTYLENE TEREPHTHALATE) COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF CITIBANK, N.A., AS COLLATERAL AGENT 2010-07-01 US disclosed