Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 9/20 | 0.39 |
| ▸ | THRB | P10828 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695481 | 0.91 | THRA (0.37) | THRATHRBPIN1HIF1A | |
| SCHEMBL6697155 | 0.86 | L3MBTL1 (0.39) | THRATHRBALDH1A1HIF1A | |
| SCHEMBL6694254 | 0.86 | CA12 (0.34) | THRATHRBALDH1A1PIN1 | |
| SCHEMBL6692436 | 0.86 | ATM (0.39) | THRATHRB | |
| SCHEMBL6699450 | 0.84 | THRB (0.39) | THRATHRBALDH1A1PIN1 | |
| SCHEMBL6693202 | 0.83 | THRA (0.54) | THRATHRB | |
| Methane SCHEMBL6690821 | 0.82 | THRA (0.53) | THRATHRB | |
| SCHEMBL6695738 | 0.80 | THRB (0.53) | THRATHRB | |
| SCHEMBL6692015 | 0.80 | THRB (0.47) | THRATHRBPIN1 | |
| SCHEMBL6695033 | 0.78 | THRB (0.59) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003094845-A2 | PYRIDINE-BASED THYROID RECEPTOR LIGANDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-11-20 | — | — | WO | disclosed |