Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.50 |
| ▸ | GABRD | O14764 | 2/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.50 |
| ▸ | GABRE | P78334 | 2/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.50 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29035549 | 0.98 | GABRP (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7930896 | 0.89 | GABRP (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7925069 | 0.87 | AKR1B1 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9517412 | 0.86 | AKR1B1 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL25694176 | 0.85 | FFAR4 (0.50) | AKR1B1FFAR4LMNAFFAR1ALDH1A1 | |
| SCHEMBL28513621 | 0.83 | FFAR4 (0.48) | AKR1B1FFAR4LMNAFFAR1ALDH1A1 | |
| SCHEMBL27969304 | 0.83 | FFAR4 (0.53) | AKR1B1FFAR4LMNAFFAR1ALDH1A1 | |
| SCHEMBL28758843 | 0.83 | GABRP (0.34) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28556062 | 0.82 | FFAR3 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11785584 | 0.81 | ALDH1A1 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112694608-B | Six-arm polyethylene glycol derivative, preparation method and modified biological related substance | 厦门赛诺邦格生物科技股份有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-115010915-B | Nitrogen-branched nine-arm polyethylene glycol derivative, preparation method and modified biologically-relevant substance thereof | 厦门赛诺邦格生物科技股份有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111542557-B | Conjugated diene rubber | 日本瑞翁株式会社 | 2023-03-28 | — | — | CN | disclosed |
| CN-112119118-B | Rubber composition for tire tread and pneumatic tire | 横滨橡胶株式会社 | 2023-03-10 | — | — | CN | disclosed |
| CN-112166149-B | Rubber composition for winter tire tread and winter pneumatic tire | 横滨橡胶株式会社 | 2023-02-28 | — | — | CN | disclosed |
| CN-112119117-B | Rubber composition for tire tread and pneumatic tire | 横滨橡胶株式会社 | 2023-02-21 | — | — | CN | disclosed |
| CN-112135873-B | Rubber composition for tire tread and pneumatic tire | 横滨橡胶株式会社 | 2023-02-17 | — | — | CN | disclosed |
| CN-115698172-A | Rubber composition for tire and tire | 横滨橡胶株式会社 | 2023-02-03 | — | — | CN | disclosed |
| CN-115667397-A | Rubber composition for tire and tire | 横滨橡胶株式会社 | 2023-01-31 | — | — | CN | disclosed |
| CN-114436809-B | Method for preparing diethyl maleate by carrying out depolymerization on lignin under catalysis of iron oxide loaded by USY molecular sieve | 华南理工大学 | 2023-01-06 | — | — | CN | disclosed |
| US-20180273595-A1 | ERG TARGETED THERAPY | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2018-09-27 | — | — | US | disclosed |
| WO-2018175273-A1 | ERG TARGETED THERAPY | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-09-27 | — | — | WO | disclosed |
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2018-08-02 | — | — | US | disclosed |
| EP-3315531-A1 | 8-ARM POLYETHYLENE GLYCOL DERIVATIVE, MANUFACTURING METHOD AND MODIFIED BIO-RELATED SUBSTANCE THEREBY | Xiamen Sinopeg Biotech Co., Ltd. (CN) | 2018-05-02 | — | — | EP | disclosed |
| CN-1897931-A | Inhibitors of cathepsin s | IRM LLC (BM) | 2007-01-17 | — | — | CN | disclosed |
| EP-1067935-B1 | ACYLBENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE(S) | UNIV CALIFORNIA (US) | 2003-08-20 | — | — | EP | disclosed |
| EP-1067935-A4 | ACYLBENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE(S) | UNIV CALIFORNIA (US) | 2001-10-04 | — | — | EP | disclosed |
| EP-1067935-A1 | ACYLBENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE(S) | The Regents of the University of California (US) | 2001-01-17 | — | — | EP | disclosed |
| US-6124278-A | COGNITION ACTIVATORS FOR LEARNING/MEMORY ENHANCEMENT AND TREATMENT OF BRAIN/PSYCHOLOGICAL DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-09-26 | — | — | US | disclosed |
| WO-1999051240-A1 | ACYLBENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | MRPL38, CXCL8, ALG8 | GABRP 1197/4885GABRD 1277/4885GABRA1 862/4885 |
| US-20180273595-A1 | ERG TARGETED THERAPY | ERG, EWSR1, ETV1 | GABRP 2584/4885GABRD 1836/4885GABRA1 2968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.