SCHEMBL7258587

SCHEMBL7258587

CC1(C)Oc2cc(Cl)ccc2C2OC21

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KCNE1 P15382 1/20 0.38
KCNQ1 P51787 1/20 0.38
KCNH2 Q12809 7/20 0.38
ABCC9 O60706 5/20 0.36
IDO1 P14902 2/20 0.36
MAP3K14 Q99558 1/20 0.35
AHR P35869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL482484 0.87 KCNE1 (0.47) KCNE1KCNQ1KCNH2ABCC9
SCHEMBL482676 0.79 ABCC9 (0.37) ABCC9IDO1AHR
SCHEMBL482485 0.79 ABCC9 (0.37) ABCC9IDO1AHR
SCHEMBL9789591 0.78 LTB4R (0.39) IDO1
SCHEMBL9789590 0.78 LTB4R (0.39) IDO1
SCHEMBL9789592 0.78 LTB4R (0.39) IDO1
SCHEMBL13380562 0.77 IDO1 (0.44) KCNE1KCNQ1IDO1
SCHEMBL7253544 0.77 IDO1 (0.44) KCNE1KCNQ1IDO1
SCHEMBL9753193 0.76 TRPV1 (0.36) IDO1
SCHEMBL12961911 0.75 TSHR (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003014113-A1 NOVEL BENZOPYRAN COMPOUNDS AND PROCESS FOR THEIR PREPARATION AND USE GLENMARK PHARMACEUTICALS LIMITED (IN) 2003-02-20 WO disclosed