Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.46 |
| ▸ | THRB | P10828 | 6/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258641 | 0.79 | RORC (0.49) | RORCTHRBTHRA | |
| SCHEMBL8062067 | 0.71 | RORC (0.51) | RORCTHRBTHRA | |
| SCHEMBL6691996 | 0.70 | RORC (0.55) | RORCTHRBTHRA | |
| SCHEMBL22959176 | 0.68 | RORC (0.70) | RORCTHRBTHRA | |
| SCHEMBL22959162 | 0.68 | RORC (0.70) | RORCTHRBTHRA | |
| SCHEMBL6694690 | 0.68 | RORC (0.56) | RORCTHRBTHRA | |
| SCHEMBL282476 | 0.68 | RORC (0.66) | RORCTHRBTHRA | |
| SCHEMBL6367085 | 0.67 | RORC (0.62) | RORCTHRBLPAR1 | |
| SCHEMBL11206396 | 0.67 | KDM4E (0.56) | RORCTHRBLPAR1 | |
| SCHEMBL8799780 | 0.67 | RORC (0.68) | RORCTHRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003094845-A2 | PYRIDINE-BASED THYROID RECEPTOR LIGANDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-11-20 | — | — | WO | disclosed |