SCHEMBL725899

SCHEMBL725899

C/N=C(\N(C)C)N(C)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.45
PHGDH O43175 1/20 0.45
MGLL Q99685 1/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
LMNA P02545 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
KMT2A Q03164 5/20 0.39
POLB P06746 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 3/20 0.38
ALDH1A1 P00352 2/20 0.38
SIGMAR1 Q99720 1/20 0.38
HTT P42858 2/20 0.37
MAPT P10636 1/20 0.35
RAB9A P51151 2/20 0.35
PKM P14618 1/20 0.35
NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL725900 1.00 FAAH (0.45) FAAHPHGDHMGLLCA12CA1
SCHEMBL25137294 0.91 FAAH (0.48) FAAHPHGDHMGLLCA12CA1
SCHEMBL4008655 0.79 CHRM5 (0.46) KMT2APOLBKDM4EMEN1ALDH1A1
SCHEMBL4008657 0.79 CHRM5 (0.46) KMT2APOLBKDM4EMEN1ALDH1A1
SCHEMBL3441588 0.76 POLB (0.40) FAAHPHGDHMGLLCA12CA1
SCHEMBL10818009 0.76 FAAH (0.47) FAAHPHGDHMGLLCA12CA1
SCHEMBL21096030 0.76 FAAH (0.47) FAAHPHGDHMGLLCA12CA1
SCHEMBL14220039 0.74 FAAH (0.45) FAAHPHGDHMGLLCA12CA1
SCHEMBL23517155 0.74 SIGMAR1 (0.53) FAAHPHGDHMGLLCA12CA1
SCHEMBL29661714 0.74 FAAH (0.45) FAAHPHGDHMGLLCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4225822-B1 METHOD FOR PRODUCING POLYURETHANE FOAMS OR HYDROGELS BY EMPLOYING DIOL CONTAINING FORMULATIONS COVESTRO DEUTSCHLAND AG (DE) 2026-05-13 EP disclosed
EP-3582816-B1 METHOD FOR PRODUCING AN ADHESIVE-FREE WOUND CONTACT MATERIAL COVESTRO DEUTSCHLAND AG (DE) 2024-10-30 EP disclosed
EP-3737429-B1 METHOD FOR THE MANUFACTURE OF ELASTIC AND TEAR-RESISTANT POLYURETHANE FOAMS AND THEIR APPLICATIONS COVESTRO DEUTSCHLAND AG (DE) 2024-03-20 EP disclosed
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20230416446-A1 Method for Producing Polyurethane Foams or Hydrogels by Employing Diol Containing Formulations COVESTRO DEUTSCHLAND AG (DE) 2023-12-28 US disclosed
CN-116981709-A Method for producing polyurethane foam or hydrogel by using diol-containing formulation 科思创德国股份有限公司 2023-10-31 CN disclosed
US-11730853-B2 Method for producing an adhesive-free wound contact composite material COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2023-08-22 US disclosed
EP-4225822-A1 METHOD FOR PRODUCING POLYURETHANE FOAMS OR HYDROGELS BY EMPLOYING DIOL CONTAINING FORMULATIONS Covestro Deutschland AG (DE) 2023-08-16 EP disclosed
US-20230120996-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-20 US disclosed
EP-2336211-A1 Hydrophilic aliphatic polyurethane foams Bayer MaterialScience AG (DE) 2011-06-22 EP disclosed
WO-2011069972-A2 HYDROPHILIC, ALIPHATIC POLYURETHANE FOAMS BAYER MATERIALSCIENCE AG (DE) 2011-06-16 WO disclosed
EP-2300510-A1 HYDROPHILIC, ALIPHATIC POLYURETHANE FOAMS Bayer MaterialScience AG (DE) 2011-03-30 EP disclosed
EP-2289959-A1 Hydrophilic aliphatic polyurethane foams Bayer Material Science AG (DE) 2011-03-02 EP disclosed
WO-2011006608-A1 METHOD FOR PRODUCING FLAT, HYDROPHILIC, ALIPHATIC POLYURETHANE FOAM MATERIALS BAYER MATERIALSCIENCE AG (DE) 2011-01-20 WO disclosed
WO-2010003559-A1 HYDROPHILIC, ALIPHATIC POLYURETHANE FOAMS BAYER MATERIALSCIENCE AG (DE) 2010-01-14 WO disclosed
EP-2143744-A1 Hydrophilic aliphatic polyurethane foams Bayer MaterialScience AG (DE) 2010-01-13 EP disclosed
EP-1208082-B1 IMPROVED METHOD FOR PRODUCING MONOISOCYANATES AND OLIGOISOCYANATES BASF AG (DE) 2004-04-07 EP disclosed
US-6683204-B1 PHOSGENATION OF PRIMARY AMINES; CATALYSIS USING MONOISOCYANATE BASF AKTIENGESELLSCHAFT (DE) 2004-01-27 US disclosed
US-4191815-A DIAZABICYCLOALKENE, GUANIDINE, AND BIGUANIDINE CATALYSTS S.A. PRB (BE) 1980-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP FAAH 2818/4885PHGDH 1455/4885MGLL 62/4885
US-20230120996-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP FAAH 2818/4885PHGDH 1455/4885MGLL 62/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.