Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.58 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16938643 | 0.87 | PRMT1 (0.64) | EPHX2PRMT1PLA2G2AECE1ITGB3 | |
| SCHEMBL14980387 | 0.86 | EPHX1 (0.56) | EPHX2PRMT1PLA2G2AECE1ITGB3 | |
| SCHEMBL18724795 | 0.83 | EPHX2 (0.81) | EPHX2PRMT1PLA2G2AEPHX1 | |
| SCHEMBL15743121 | 0.83 | EPHX2 (0.81) | EPHX2PRMT1PLA2G2AEPHX1 | |
| SCHEMBL18724674 | 0.83 | EPHX2 (0.81) | EPHX2PRMT1PLA2G2AEPHX1 | |
| SCHEMBL23173031 | 0.82 | EPHX1 (0.52) | EPHX2PRMT1EPHX1NOS2 | |
| SCHEMBL4856595 | 0.79 | NOS2 (0.44) | EPHX2PRMT1ECE1EPHX1NOS2 | |
| SCHEMBL28293734 | 0.79 | MMP1 (0.48) | EPHX2EPHX1 | |
| SCHEMBL320068 | 0.79 | — | — | |
| SCHEMBL8361994 | 0.79 | EPHX1 (0.76) | EPHX2PRMT1PLA2G2AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003066624-A1 | PYRIMIDINONESULFAMOYLUREAS AS INTEGRIN LIGANDS | ABBOTT GMBH & CO. KG (DE) | 2003-08-14 | — | — | WO | disclosed |