Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720230 | 0.78 | KCNH2 (0.35) | EGFRROCK1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL16720510 | 0.78 | EGFR (0.37) | EGFRROCK1CYP3A4ALDH1A1MAPT | |
| SCHEMBL16720122 | 0.78 | ALDH1A1 (0.39) | ROCK1PDGFRBPDGFRACA12CA1 | |
| SCHEMBL16719859 | 0.77 | FGFR1 (0.43) | EGFRROCK1CYP1A2ALDH1A1 | |
| SCHEMBL16720196 | 0.75 | GAA (0.42) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL16720394 | 0.75 | MAPT (0.35) | MAPTTUBB1 | |
| SCHEMBL16719889 | 0.75 | CYP11B1 (0.40) | ROCK1CYP1A2CYP3A4MAPT | |
| SCHEMBL7264816 | 0.74 | EGFR (0.38) | EGFRCYP1A2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL16720522 | 0.74 | TRPV4 (0.33) | EGFRALDH1A1 | |
| SCHEMBL16719332 | 0.74 | HTR6 (0.36) | MAPTTUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6646009-B2 | Use against proliferative disorders including cancer, and as a radioprotective compound for normal cells from ionizing radiation | Temple University — Of Commonwealth System of Higher Education | 2003-11-11 | — | — | US | disclosed |