Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | DDX3X | O00571 | 1/20 | 0.42 |
| ▸ | EIF4E | P06730 | 3/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259179 | 0.85 | ALDH1A1 (0.47) | TSHRHTTLMNAMAPTNPSR1 | |
| SCHEMBL7254049 | 0.85 | LMNA (0.42) | TSHRHTTLMNAMAPTPARP1 | |
| SCHEMBL7717021 | 0.84 | MGAM (0.54) | TSHRHTTLMNAMAPTNPSR1 | |
| SCHEMBL7259712 | 0.80 | PARP1 (0.47) | LMNAMAPTPARP1ALDH1A1DHODH | |
| SCHEMBL7718394 | 0.79 | HSD11B1 (0.42) | HTTLMNAMAPTNPSR1HSD11B1 | |
| SCHEMBL7713526 | 0.79 | MGAM (0.44) | HTTLMNAMAPTNPSR1HSD11B1 | |
| SCHEMBL6514322 | 0.77 | ALDH1A1 (0.62) | TSHRHTTLMNAMAPTHSD11B1 | |
| SCHEMBL7254390 | 0.77 | PARP1 (0.46) | PARP1ALDH1A1DHODH | |
| SCHEMBL505230 | 0.76 | DHODH (0.63) | NPSR1PARP1ALDH1A1GAADHODH | |
| SCHEMBL7719043 | 0.75 | HSD11B1 (0.39) | HTTLMNAMAPTNPSR1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057667-A2 | STRAPPED AND MODIFIED BIS (BENZIMIDAZOLE) DIAMIDES FOR ASYMMETRIC CATALYSTS AND OTHER APPLICATIONS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2003-07-17 | — | — | WO | disclosed |