SCHEMBL7259245

SCHEMBL7259245

N#Cc1cnn(-c2ccc(CC(=O)O)cc2)c1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
QPCT Q16769 1/20 0.45
GCGR P47871 1/20 0.44
NSD2 O96028 1/20 0.43
POLB P06746 1/20 0.43
GRK2 P25098 1/20 0.43
CASP6 P55212 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
ACACB O00763 1/20 0.42
KLKB1 P03952 1/20 0.42
CTSB P07858 1/20 0.42
RXRA P19793 1/20 0.41
RXRG P48443 1/20 0.41
ALKBH1 Q13686 1/20 0.41
FFAR1 O14842 1/20 0.41
EGLN1 Q9GZT9 1/20 0.40
LMNA P02545 1/20 0.40
CTBP2 P56545 1/20 0.39
FFAR4 Q5NUL3 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21753313 0.82 NOTUM (0.48) GCGRACACBALKBH1EGLN1
SCHEMBL21525502 0.81 HPGDS (0.53) GCGR
SCHEMBL21753342 0.79 CYP19A1 (0.40) GCGRACACB
SCHEMBL11492464 0.78 MEN1 (0.49) QPCTNSD2POLBGRK2CASP6
SCHEMBL11493879 0.78 QPCT (0.49) QPCTGCGRNSD2POLBGRK2
SCHEMBL11486254 0.78 QPCT (0.49) QPCTGCGRNSD2POLBGRK2
SCHEMBL1682507 0.77 CA12 (0.47) GCGR
SCHEMBL2214866 0.76 GAA (0.53) ACACB
SCHEMBL31517446 0.76 GRM5 (0.50) POLBALKBH1FFAR1LMNAFFAR4
SCHEMBL335492 0.74 CTBP2 (0.62) RXRARXRGFFAR1LMNACTBP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003059903-A2 SUBSTITUTED 4-AMINOPYRIDINE DERIVATIVES USED AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-07-24 WO disclosed