SCHEMBL335492

SCHEMBL335492

N#Cc1ccc(CC(=O)O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTBP2 P56545 1/20 0.62
FFAR1 O14842 1/20 0.62
HTT P42858 2/20 0.59
CA2 P00918 2/20 0.56
CAMK2A Q9UQM7 1/20 0.56
RXRA P19793 2/20 0.54
RXRG P48443 2/20 0.54
AKR1B1 P15121 1/20 0.54
ABCC4 O15439 1/20 0.52
LMNA P02545 1/20 0.52
GAA P10253 1/20 0.52
TSHR P16473 1/20 0.52
PTGS1 P23219 1/20 0.52
LOXL2 Q9Y4K0 2/20 0.50
CYP2A6 P11509 1/20 0.50
SAE1 Q9UBE0 1/20 0.50
UBA2 Q9UBT2 1/20 0.50
MMP12 P39900 1/20 0.50
MMP13 P45452 1/20 0.50
RXRB P28702 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29236556 0.98 CTBP2 (0.61) CTBP2FFAR1HTTCA2CAMK2A
Hydrochloric Acid SCHEMBL7981327 0.98 CTBP2 (0.61) CTBP2FFAR1HTTCA2CAMK2A
SCHEMBL8185095 0.94 HTT (0.62) CTBP2FFAR1HTTCA2CAMK2A
SCHEMBL6540182 0.89 MAOB (0.56) CTBP2FFAR1HTTCA2CAMK2A
SCHEMBL6917099 0.89 SRD5A2 (0.57) CTBP2FFAR1HTTCA2CAMK2A
SCHEMBL6937899 0.84 CTBP2 (0.59) CTBP2FFAR1HTTCA2LOXL2
SCHEMBL10275551 0.84 CTBP2 (0.56) CTBP2FFAR1HTTCA2RXRA
SCHEMBL6670974 0.83 CTBP2 (0.64) CTBP2FFAR1HTTCA2LOXL2
SCHEMBL6564262 0.83 CTBP2 (0.58) CTBP2FFAR1HTTCA2LOXL2
SCHEMBL9641208 0.82 CTBP2 (0.57) CTBP2FFAR1HTTAKR1B1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 612 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112939748-A Method for preparing deuterated compound through decarboxylation and deuteration of carboxylic acid 中国科学院大连化学物理研究所 2021-06-11 CN claimed
US-8609882-B2 Process for deacetalisation of α aminoacetals CLARIANT SPECIALITY FINE CHEMICALS (FRANCE) (FR) 2013-12-17 US claimed
EP-2137139-A1 PROCESS OF DEACETALISATION OF ALPHA AMINOACETALS Clariant Specialty Fine Chemicals (France) (FR) 2009-12-30 EP claimed
WO-2008125486-A1 PROCESS OF DEACETALISATION OF ALPHA AMINOACETALS CLARIANT SPECIALTY FINE CHEMICALS (FRANCE) (FR) 2008-10-23 WO claimed
EP-4727537-A2 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF Adaxion Therapeutics, Inc. (US) 2026-04-22 EP disclosed
US-12606548-B2 Fungicidal oxadiazoles FMC CORPORATION (US) 2026-04-21 US disclosed
EP-4722200-A1 COMPOUND, METHOD FOR PREPARING SAME, AND CROSSLINKING AGENT, PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, AND ELECTRONIC DEVICE, COMPRISING SAME LG Chem, Ltd. (KR) 2026-04-08 EP disclosed
US-20260070920-A1 N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES AND USES THEREOF NOVARTIS AG (CH) 2026-03-12 US disclosed
US-20250353820-A1 ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS NOVARTIS AG (CH) 2025-11-20 US disclosed
EP-4169925-B1 PROCESS TO MAKE N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES NOVARTIS AG (CH) 2025-11-19 EP disclosed
US-20250326764-A1 INHIBITORS OF THE MENIN-MLL INTERACTION VITAE PHARMACEUTICALS LLC (US) 2025-10-23 US disclosed
US-20250295652-A1 Inhibitors of Molluscum Contagiosum Infection and Methods Using the Same UNIV PENNSYLVANIA (US) 2025-09-25 US disclosed
EP-0168467-A1 NOVEL ARYLACETIC ACID DERIVATIVES PHARMACIA AB (SE) 1986-01-22 EP disclosed
WO-1985003287-A1 NOVEL ARYLACETIC ACID DERIVATIVES PHARMACIA AB (SE) 1985-08-01 WO disclosed
EP-0150166-A1 Novel arylacitic acid derivatives PHARMACIA AB (SE) 1985-07-31 EP disclosed
EP-0058779-B1 CARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS MEDICINES Dr. Karl Thomae GmbH (DE) 1984-09-19 EP disclosed
EP-0099017-A2 Phenyl-acetic-acid derivatives, their preparation and pharmaceutical compostions containing them Dr. Karl Thomae GmbH (DE) 1984-01-25 EP disclosed
US-4405705-A HYDROPHILIC TOYO BOSEKI KABUSHIKI KAISHA T/A TOYOBA CO., LTD. (JP) 1983-09-20 US disclosed
EP-0058779-A2 Carboxamides, their preparation and their use as medicines Dr. Karl Thomae GmbH (DE) 1982-09-01 EP disclosed
US-3945888-A AMIDATION, ENZYMES OF ESCHERICHIA, BACILLUS, PROTEUS TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250295652-A1 Inhibitors of Molluscum Contagiosum Infection and Methods Using the Same ITCH, EIF2AK2, TBK1 CTBP2 2618/4885FFAR1 4876/4885HTT 4348/4885
US-12606548-B2 Fungicidal oxadiazoles AOC2, AOC3, MT-CO3 CTBP2 3424/4885FFAR1 2073/4885HTT 2982/4885
US-20250353820-A1 ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS ZC3HAV1, TYMP, ZC3HAV1L CTBP2 4770/4885FFAR1 4201/4885HTT 3477/4885
US-20260070920-A1 N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES AND USES THEREOF CCR3, SCN1B, NR3C1 CTBP2 2064/4885FFAR1 1693/4885HTT 3016/4885
US-20250326764-A1 INHIBITORS OF THE MENIN-MLL INTERACTION MLLT1, MEN1, MLLT3 CTBP2 1164/4885FFAR1 4367/4885HTT 2985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.