Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 5/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541103 | 0.73 | HPGD (0.42) | ALDH1A1POLB | |
| SCHEMBL10086564 | 0.71 | KCNA5 (0.56) | ACHEDRD2HTR2ASIGMAR1ALDH1A1 | |
| SCHEMBL16299527 | 0.70 | DRD2 (0.51) | DRD2HTR2ASIGMAR1CNR2ALDH1A1 | |
| SCHEMBL16314493 | 0.70 | DRD2 (0.51) | CA1CA2DRD2HTR2ASIGMAR1 | |
| SCHEMBL15698486 | 0.69 | CA1 (0.42) | SLC2A1CA1CA2BDKRB1ACHE | |
| SCHEMBL6767339 | 0.68 | SLC2A1 (0.46) | SLC2A1CA1CA2DRD2HTR2A | |
| SCHEMBL27699518 | 0.67 | — | — | |
| SCHEMBL9434876 | 0.67 | ALOX15 (0.50) | DRD2HTR2AALDH1A1 | |
| SCHEMBL16353593 | 0.64 | ACKR3 (0.46) | SLC2A1BDKRB1SIGMAR1ACKR3 | |
| SCHEMBL26849999 | 0.64 | HRH2 (0.42) | CA1CA2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003076408-A2 | INDAZOLE DERIVATIVES THAT ARE ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | ABBOTT LABORATORIES (US) | 2003-09-18 | — | — | WO | disclosed |