SCHEMBL7259267

SCHEMBL7259267

Cc1ccc(C)c2c1C(C)N(C)C2C

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12604237 0.65
SCHEMBL8985401 0.63 HTR2C (0.34) HTR2AHTR2CHTR2B
SCHEMBL31499374 0.56 TDP1 (0.32)
SCHEMBL4160459 0.55 CYP1A2 (0.47)
SCHEMBL44351 0.54 ALDH1A1 (0.62) HTR2CHTR2B
SCHEMBL7156116 0.53 ACHE (0.40)
SCHEMBL24278676 0.53 MAP3K14 (0.34) HTR2AHTR2CHTR2B
SCHEMBL5494672 0.52 TSHR (0.45)
SCHEMBL597313 0.52 CYP1A2 (0.44)
SCHEMBL4160455 0.52 ALDH1A1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0994879-B1 PHOTOCHROMATIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN POLYMERIC MATERIALS GREAT LAKES CHEMICAL EUROP (CH) 2003-09-24 EP disclosed
US-6414057-B1 STRESS RESISTANCE, DYEABLE GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2002-07-02 US disclosed
EP-1153100-A1 PHOTOCHROMATIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN POLYMERIC MATERIALS Great Lakes Chemical (Europe) GmbH (CH) 2001-11-14 EP disclosed
EP-1110966-A2 Silyl-carbamate photochromatic compounds process for their preparation and their use in polymeric materials Great Lakes Chemical (Europe) GmbH (CH) 2001-06-27 EP disclosed
WO-2000039245-A1 PHOTOCHROMATIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN POLYMERIC MATERIALS GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2000-07-06 WO disclosed