Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7261350 | 0.73 | PTGS2 (0.46) | PTGS2PTGS1PDE4BALDH1A1MAPT | |
| SCHEMBL7260521 | 0.72 | NPC1 (0.37) | PTGS2PTGS1PDE4BALDH1A1MAPT | |
| SCHEMBL30800362 | 0.70 | TYMS (0.62) | ALDH1A1MAPTHTTNPSR1GSK3B | |
| SCHEMBL279560 | 0.70 | TYMS (0.62) | ALDH1A1MAPTHTTNPSR1GSK3B | |
| SCHEMBL114611 | 0.69 | PTGS2 (0.67) | PTGS2PDE4BGSK3B | |
| SCHEMBL532969 | 0.67 | ALDH1A1 (0.67) | PDE4BALDH1A1MAPTHTTLMNA | |
| SCHEMBL852224 | 0.67 | ALDH1A1 (0.67) | PDE4BALDH1A1MAPTHTTLMNA | |
| SCHEMBL532970 | 0.67 | ALDH1A1 (0.67) | PDE4BALDH1A1MAPTHTTLMNA | |
| SCHEMBL516326 | 0.67 | PDE4B (0.54) | PDE4BALDH1A1MAPTHTTMITF | |
| SCHEMBL9474080 | 0.67 | PTGS2 (0.64) | PTGS2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080553-A1 | CYCLOPENTENE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2003-10-02 | — | — | WO | disclosed |