Desmedipham

Desmedipham

SCHEMBL725936

CCOC(=O)Nc1cccc(OC(=O)Nc2ccccc2)c1.NC(=O)Oc1ccccc1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.59
MAPK1 P28482 3/20 0.59
HSD17B10 Q99714 2/20 0.59
LMNA P02545 1/20 0.59
RAB9A P51151 3/20 0.56
HPGD P15428 3/20 0.56
NPC1 O15118 1/20 0.56
CRHBP P24387 1/20 0.56
CRHR2 Q13324 1/20 0.56
MTNR1B P49286 1/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
ALOX15 P16050 1/20 0.56
CYP2C19 P33261 1/20 0.56
CASP3 P42574 1/20 0.56
SENP8 Q96LD8 1/20 0.56
SENP7 Q9BQF6 1/20 0.56
SENP6 Q9GZR1 1/20 0.56
ALDH1A1 P00352 5/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4290909 0.92 MTNR1B (0.60) MAPTMAPK1HSD17B10LMNARAB9A
Desmedipham SCHEMBL29516752 0.92 MAPK1 (0.68) MAPTMAPK1HSD17B10LMNARAB9A
Desmedipham SCHEMBL4895813 0.92 MAPK1 (0.68) MAPTMAPK1HSD17B10LMNARAB9A
Desmedipham SCHEMBL55084 0.92 MAPK1 (0.68) MAPTMAPK1HSD17B10LMNARAB9A
SCHEMBL4108576 0.88 MAPK1 (0.74) MAPTMAPK1HSD17B10LMNARAB9A
Desmedipham SCHEMBL3230751 0.84 MAPK1 (0.79) MAPTMAPK1HSD17B10LMNARAB9A
SCHEMBL9833721 0.84 KMT2A (0.68) MAPTMAPK1LMNARAB9ANPC1
SCHEMBL30487931 0.84 KMT2A (0.68) MAPTMAPK1LMNARAB9ANPC1
SCHEMBL134424 0.83 MAPK1 (0.77) MAPTMAPK1HSD17B10LMNARAB9A
SCHEMBL29512574 0.83 MAPK1 (0.77) MAPTMAPK1HSD17B10LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011161131-A1 HERBICIDAL MIXTURES BASF SE (DE) 2011-12-29 WO disclosed