Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | ATP4A | P20648 | 5/20 | 0.35 |
| ▸ | ATP4B | P51164 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | EIF4E | P06730 | 2/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263113 | 0.92 | ATP4A (0.35) | MAPTSMN1; SMN2HTTKDM4EMEN1 | |
| SCHEMBL7259393 | 0.87 | PSMB5 (0.33) | SMN1; SMN2MEN1KMT2ATP53MAPK1 | |
| SCHEMBL7262972 | 0.85 | HSD17B1 (0.33) | — | |
| SCHEMBL7258931 | 0.83 | HSD17B1 (0.32) | — | |
| SCHEMBL7264023 | 0.82 | FFAR1 (0.35) | HTTKDM4EALDH1A1LMNA | |
| SCHEMBL5673933 | 0.82 | ADA (0.50) | MAPTSMN1; SMN2HTTKDM4EMEN1 | |
| SCHEMBL7264650 | 0.82 | DHODH (0.34) | MAPTSMN1; SMN2HTTKDM4EMEN1 | |
| SCHEMBL7259445 | 0.82 | MAPT (0.40) | MAPTSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL7264341 | 0.82 | CHEK2 (0.35) | MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7264346 | 0.80 | ATP4A (0.38) | MAPTSMN1; SMN2HTTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | claimed |
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | disclosed |