Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 2/20 | 0.35 |
| ▸ | ATP4B | P51164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259386 | 0.92 | MAPT (0.39) | ATP4AATP4BMEN1KMT2AHTT | |
| SCHEMBL7264346 | 0.89 | ATP4A (0.38) | ATP4AATP4BMEN1KMT2ANPSR1 | |
| SCHEMBL7259393 | 0.85 | PSMB5 (0.33) | MEN1KMT2ACDK5HDAC1SMN1; SMN2 | |
| SCHEMBL5669578 | 0.83 | ADA (0.48) | ATP4AATP4BECE1CDK5CDK5R1 | |
| SCHEMBL7262972 | 0.83 | HSD17B1 (0.33) | PPARA | |
| SCHEMBL7258931 | 0.81 | HSD17B1 (0.32) | NPSR1 | |
| SCHEMBL7264023 | 0.81 | FFAR1 (0.35) | HTTPPARDALDH1A1KDM4ELMNA | |
| SCHEMBL7259445 | 0.80 | MAPT (0.40) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL7264650 | 0.80 | DHODH (0.34) | MEN1KMT2AHTTMAPTALDH1A1 | |
| SCHEMBL7264341 | 0.80 | CHEK2 (0.35) | SCN9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006437-A1 | IMIDAZOLE DERIVATIVES AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-23 | — | — | WO | claimed |