Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968650 | 0.81 | GPR3 (0.52) | GPR3PDE10APOLBALDH1A1HSD17B10 | |
| SCHEMBL23999688 | 0.79 | POLB (0.68) | GPR3PDE10APOLBALDH1A1HSD17B10 | |
| SCHEMBL1278314 | 0.72 | PDE10A (0.57) | GPR3PDE10APOLBALDH1A1HSD17B10 | |
| SCHEMBL5502106 | 0.72 | GPR3 (0.46) | GPR3PDE10APOLBALDH1A1HSD17B10 | |
| SCHEMBL231530 | 0.72 | GPR3 (0.64) | GPR3PDE10APOLBALDH1A1HSD17B10 | |
| SCHEMBL293600 | 0.71 | CYP1A2 (0.40) | ALDH1A1HSD17B10CYP1A2HPGDL3MBTL1 | |
| SCHEMBL3966414 | 0.71 | GPR3 (0.57) | GPR3PDE10APOLBALDH1A1HSD17B10 | |
| SCHEMBL27999098 | 0.70 | GPR3 (0.52) | GPR3PDE10APOLBALDH1A1HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL28822932 | 0.70 | GPR3 (0.61) | GPR3PDE10APOLBALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL27521191 | 0.70 | GPR3 (0.61) | GPR3PDE10APOLBALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003053941-A2 | BARBITURIC ACID DERIVATIVES AS INHIBITORS OF TNF-ALPHA CONVERTING ENZYME (TACE) AND/OR MATRIX METALLOPROTEINASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-07-03 | — | — | WO | disclosed |