Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999688 | 0.78 | POLB (0.68) | GPR3PDE10APOLBALDH1A1HSD17B10 | |
| SCHEMBL3968650 | 0.76 | GPR3 (0.52) | GPR3PDE10APOLBALDH1A1HSD17B10 | |
| SCHEMBL4438037 | 0.74 | ALDH1A1 (0.44) | POLBALDH1A1CYP1A2KDM4EATM | |
| SCHEMBL5502171 | 0.74 | GFER (0.42) | PDE10APOLBALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL5502639 | 0.73 | ALDH1A1 (0.43) | POLBALDH1A1CYP1A2HPGDKMT2A | |
| SCHEMBL7259506 | 0.72 | GPR3 (0.47) | GPR3PDE10APOLBALDH1A1HSD17B10 | |
| SCHEMBL1278314 | 0.71 | PDE10A (0.57) | GPR3PDE10APOLBALDH1A1HSD17B10 | |
| SCHEMBL231530 | 0.70 | GPR3 (0.64) | GPR3PDE10APOLBALDH1A1HSD17B10 | |
| SCHEMBL6215008 | 0.70 | GPR3 (0.57) | GPR3PDE10APOLBALDH1A1HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL28822932 | 0.69 | GPR3 (0.61) | GPR3PDE10APOLBALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1803150-A1 | COMPOUNDS FOR MYOCARDIAL PERFUSION IMAGING | Bristol-Myers Squibb Pharma Company (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006044280-A1 | COMPOUNDS FOR MYOCARDIAL PERFUSION IMAGING | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2006-04-27 | — | — | WO | disclosed |
| US-20060083681-A1 | Compounds for myocardial perfusion imaging | LANTHEUS MEDICAL IMAGING, INC. | 2006-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060083681-A1 | Compounds for myocardial perfusion imaging | TNNI3, FABP3, TNNT2 | GPR3 921/4885PDE10A 481/4885POLB 2376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.