Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28822932

Cc1nc2ccccc2c(C)c1C.N

nearest known ligand 0.61

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.61
PDE10A Q9Y233 1/20 0.58
ALDH1A1 P00352 4/20 0.55
CYP1A2 P05177 3/20 0.55
HSD17B10 Q99714 3/20 0.55
HPGD P15428 2/20 0.55
NUDT1 P36639 1/20 0.55
HTT P42858 2/20 0.53
KDM4E B2RXH2 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
TP53 P04637 1/20 0.46
ERN1 O75460 1/20 0.46
MAPT P10636 1/20 0.46
CASP3 P42574 1/20 0.46
BACE1 P56817 1/20 0.44
NCF1 P14598 1/20 0.44
DCPS Q96C86 1/20 0.43
POLB P06746 1/20 0.43
MAOA P21397 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL231530 0.98 GPR3 (0.64) GPR3PDE10AALDH1A1CYP1A2HSD17B10
Hydrochloric Acid SCHEMBL27521191 0.95 GPR3 (0.61) GPR3PDE10AALDH1A1CYP1A2HSD17B10
SCHEMBL27691854 0.86 PDE10A (0.54) GPR3PDE10AALDH1A1CYP1A2HSD17B10
Quinoline SCHEMBL28214297 0.83 ALDH1A1 (0.59) GPR3PDE10AALDH1A1CYP1A2HSD17B10
SCHEMBL28042218 0.83 ALDH1A1 (0.62) GPR3PDE10AALDH1A1CYP1A2HSD17B10
Ammonia Solution, Strong SCHEMBL27928855 0.81 MAOA (0.59) GPR3PDE10AALDH1A1CYP1A2HSD17B10
SCHEMBL31678400 0.80 GPR3 (0.58) GPR3PDE10AALDH1A1CYP1A2HSD17B10
SCHEMBL50940 0.80 GPR3 (0.58) GPR3PDE10AALDH1A1CYP1A2HSD17B10
SCHEMBL27296318 0.80 ALDH1A1 (0.64) GPR3PDE10AALDH1A1CYP1A2HSD17B10
SCHEMBL30025532 0.80 ALDH1A1 (0.64) GPR3PDE10AALDH1A1CYP1A2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114938648-A Stable bulk polymerized polycyclic olefin compositions as three-dimensional printing materials and methods of making same 普罗米鲁斯有限责任公司 2022-08-23 CN claimed
CN-118084869-A Abeta based on chemical excitation oxidation1-42Protein nanoparticle, and preparation method and application thereof 华南理工大学 2024-05-28 CN disclosed
CN-116848170-A Photoactive bulk polymerized polycycloolefin compositions as optical materials that are shelf-life stable for extended periods of time 普罗米鲁斯有限责任公司 2023-10-03 CN disclosed
CN-115052914-B Shelf life-extended bulk polymerized polycycloolefin compositions as optical materials 住友电木株式会社 2023-06-30 CN disclosed
CN-114938648-B Stable bulk polymerized polycycloolefin compositions as three-dimensional printing materials and methods of making same 住友电木株式会社 2023-06-30 CN disclosed
CN-115052914-A Shelf life extended bulk polymerized polycycloolefin compositions as optical materials 普罗米鲁斯有限责任公司 2022-09-13 CN disclosed
CN-114938648-A Stable bulk polymerized polycyclic olefin compositions as three-dimensional printing materials and methods of making same 普罗米鲁斯有限责任公司 2022-08-23 CN disclosed