Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7260755 | 0.82 | ALDH1A1 (0.46) | ALDH1A1NPSR1 | |
| SCHEMBL7260923 | 0.77 | KDM4E (0.38) | CYP1A2KMT2ACPA1MEN1CYP2C9 | |
| SCHEMBL7255971 | 0.75 | NR1H4 (0.32) | HPGDCYP1A2KMT2AMEN1POLB | |
| SCHEMBL7258559 | 0.73 | KMT2A (0.40) | KMT2AMEN1POLBPDE4BPDE4D | |
| SCHEMBL3059132 | 0.69 | ALDH1A1 (0.62) | HPGDCYP1A2KMT2AMEN1POLB | |
| SCHEMBL7258691 | 0.67 | ALDH1A1 (0.39) | HPGDKMT2ACPA1MEN1POLB | |
| SCHEMBL7255066 | 0.65 | ALDH1A1 (0.36) | HPGDCPA1ALDH1A1RAB9ANPC1 | |
| SCHEMBL7255178 | 0.65 | ALDH1A1 (0.48) | HPGDKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL24339594 | 0.64 | ALDH1A1 (0.56) | HPGDKMT2AMEN1POLBGAA | |
| SCHEMBL29610955 | 0.64 | PTPN1 (0.71) | HPGDCYP1A2KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099812-A1 | PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 2003-12-04 | — | — | WO | disclosed |