Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258550 | 0.93 | KMT2A (0.40) | KMT2AMEN1NPC1MAPTALDH1A1 | |
| SCHEMBL7255971 | 0.80 | NR1H4 (0.32) | KMT2AMEN1MAPTALDH1A1POLB | |
| SCHEMBL7260923 | 0.78 | KDM4E (0.38) | KMT2AMEN1MAPTALDH1A1FNTA | |
| SCHEMBL7259659 | 0.73 | HPGD (0.35) | KMT2AMEN1NPC1MAPTALDH1A1 | |
| SCHEMBL7255066 | 0.71 | ALDH1A1 (0.36) | NPC1ALDH1A1FNTA | |
| SCHEMBL7258565 | 0.70 | ALDH1A1 (0.39) | KMT2AMEN1NPC1MAPTATM | |
| SCHEMBL2026125 | 0.70 | MAPT (0.65) | KMT2AMEN1NPC1MAPTATM | |
| SCHEMBL7258691 | 0.69 | ALDH1A1 (0.39) | KMT2AMEN1ALDH1A1POLBFNTA | |
| SCHEMBL7255242 | 0.68 | PDK1 (0.41) | KMT2AMEN1NPC1MAPTALDH1A1 | |
| SCHEMBL7260731 | 0.63 | GAA (0.55) | NPC1MAPTALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099812-A1 | PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 2003-12-04 | — | — | WO | disclosed |