Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | RAB9A | P51151 | 4/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.77 |
| ▸ | NPC1 | O15118 | 3/20 | 0.77 |
| ▸ | LMNA | P02545 | 3/20 | 0.77 |
| ▸ | PKM | P14618 | 1/20 | 0.77 |
| ▸ | HPGD | P15428 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7255383 | 0.87 | RAB9A (1.00) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9479038 | 0.85 | MAPT (0.77) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| Bromide SCHEMBL9478404 | 0.84 | MAPT (0.76) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7259709 | 0.82 | SCN5A (0.53) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL31349243 | 0.79 | MAPT (0.68) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7256227 | 0.78 | PDE4B (0.67) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4048361 | 0.77 | RAB9A (0.73) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL31349239 | 0.77 | ALDH1A1 (0.65) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9478006 | 0.77 | TDP1 (0.67) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL3145322 | 0.77 | CA12 (0.62) | MAPTALDH1A1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099812-A1 | PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 2003-12-04 | — | — | WO | disclosed |