Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 3/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.53 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7255114 | 0.86 | NPC1 (0.67) | SCN5ASCN2ASCN10ANPC1RAB9A | |
| SCHEMBL2030346 | 0.84 | NPC1 (0.55) | SCN5ASCN2ASCN10ANPC1RAB9A | |
| SCHEMBL7259662 | 0.82 | MAPT (0.77) | SCN5ASCN2ASCN10ANPC1RAB9A | |
| SCHEMBL7255163 | 0.78 | RAB9A (0.55) | NPC1RAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1772275 | 0.75 | ERN1 (0.60) | SCN5ASCN2ASCN10ANPC1RAB9A | |
| SCHEMBL4050262 | 0.74 | RAB9A (0.52) | SCN5ASCN2ASCN10ANPC1RAB9A | |
| SCHEMBL3152770 | 0.74 | HPGD (0.69) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E | |
| SCHEMBL31098651 | 0.74 | GAA (0.67) | ALDH1A1SMN1; SMN2HPGDTDP1PDE4B | |
| SCHEMBL3451824 | 0.72 | RAB9A (0.50) | SCN5ASCN2ASCN10ANPC1RAB9A | |
| SCHEMBL3418331 | 0.72 | ALDH1A1 (0.70) | ALDH1A1LMNAHPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099812-A1 | PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 2003-12-04 | — | — | WO | disclosed |