SCHEMBL725970

SCHEMBL725970

[c]1cccc2c1C=C1C2=Nc2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.36
IDO1 P14902 1/20 0.36
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
APAF1 O14727 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
HSP90AA1 P07900 1/20 0.32
HSP90AB1 P08238 1/20 0.32
MAPT P10636 1/20 0.32
TSHR P16473 1/20 0.32
HK1 P19367 1/20 0.32
GALK1 P51570 1/20 0.32
KMT2A Q03164 1/20 0.32
HKDC1 Q2TB90 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30019213 0.72 ABCG2 (0.62) ABCG2IDO1KDM4EMEN1APAF1
SCHEMBL261676 0.72 ABCG2 (0.62) ABCG2IDO1KDM4EMEN1APAF1
SCHEMBL725971 0.70 ABCG2 (0.51) ABCG2IDO1
SCHEMBL25254164 0.67
SCHEMBL4507290 0.67 ABCG2 (0.37) ABCG2IDO1KDM4EMEN1APAF1
SCHEMBL4499072 0.66 ABCG2 (0.46) ABCG2IDO1KDM4EMEN1APAF1
SCHEMBL1899426 0.66 ABCG2 (0.40) ABCG2IDO1KDM4EMEN1APAF1
SCHEMBL4313632 0.66 ABCG2 (0.40) ABCG2IDO1KDM4EMEN1APAF1
SCHEMBL28246158 0.66 ABCG2 (0.40) ABCG2IDO1KDM4EMEN1APAF1
SCHEMBL1820364 0.66 ABCG2 (0.40) ABCG2IDO1KDM4EMEN1APAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4829498-B2 2011-12-07 JP claimed
US-7868197-B2 Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-01-11 US claimed
EP-1960442-A1 HALOGEN SUBSTITUTED HETEROATOM-CONTAINING METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2008-08-27 EP claimed
WO-2007070046-A1 HALOGEN SUBSTITUTED HETEROATOM-CONTAINING METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-06-21 WO claimed
US-20070135623-A1 Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US claimed
US-20070032619-A1 Olefin polymerization methods EQUISTAR CHEMICALS, LP 2007-02-08 US claimed
JP-2006502252-A 2006-01-19 JP claimed
EP-1525228-A2 CATALYSTS AND PROCESS FOR MAKING POLYOLEFINS Equistar Chemicals, LP (US) 2005-04-27 EP claimed
EP-1497343-A1 METHOD FOR POLYMERISATION OF OLEFINS WITH INDENO-INDOLYL CATALYSTS Equistar Chemicals, LP (US) 2005-01-19 EP claimed
US-6838410-B2 Catalysts for making polyolefins EQUISTAR CHEMICALS, LP (US) 2005-01-04 US claimed
WO-2004013194-A2 CATALYSTS AND PROCESS FOR MAKING POLYOLEFINS EQUISTAR CHEMICALS, LP (US) 2004-02-12 WO claimed
US-20040023791-A1 Catalysts for making polyolefins EQUISTAR CHEMICALS, LP 2004-02-05 US claimed
WO-2003089485-A1 METHOD FOR POLYMERISATION OF OLEFINS WITH INDENO-INDOLYL CATALYSTS EQUISTAR CHEMICALS, LP (US) 2003-10-30 WO claimed
US-20030195306-A1 Method for making polyolefins EQUISTAR CHEMICALS, LP 2003-10-16 US claimed
US-11999763-B2 Organometallic complex, olefin polymerization catalyst system and polymerization process NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2024-06-04 US disclosed
US-20240124502-A1 ORGANOMETALLIC COMPLEX, OLEFIN POLYMERIZATION CATALYST SYSTEM AND POLYMERIZATION PROCESS NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2024-04-18 US disclosed
WO-2023187552-A1 ORGANOMETALLIC COMPLEX, OLEFIN POLYMERIZATION CATALYST SYSTEM AND POLYMERIZATION PROCESS NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2023-10-05 WO disclosed
US-20030229188-A1 High-temperature solution process for polyolefin manufacture EQUISTAR CHEMICALS, LP 2003-12-11 US disclosed
WO-2003089485-A1 METHOD FOR POLYMERISATION OF OLEFINS WITH INDENO-INDOLYL CATALYSTS EQUISTAR CHEMICALS, LP (US) 2003-10-30 WO disclosed
US-20030195306-A1 Method for making polyolefins EQUISTAR CHEMICALS, LP 2003-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135623-A1 Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization OPRM1, POLM, AP1M1 ABCG2 3765/4885IDO1 3286/4885KDM4E 4141/4885
US-20240124502-A1 ORGANOMETALLIC COMPLEX, OLEFIN POLYMERIZATION CATALYST SYSTEM AND POLYMERIZATION PROCESS CYC1, CYP4F12, COASY ABCG2 3872/4885IDO1 1631/4885KDM4E 4420/4885
US-11999763-B2 Organometallic complex, olefin polymerization catalyst system and polymerization process CYC1, CYP4F12, COASY ABCG2 3872/4885IDO1 1631/4885KDM4E 4420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.