Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 6/20 | 0.33 |
| ▸ | DRD3 | P35462 | 4/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21620884 | 0.78 | KDM4E (0.42) | KDM4EHSD11B1KMT2ADRD2DRD3 | |
| SCHEMBL15077206 | 0.73 | EPAS1 (0.38) | DRD2DRD3DRD4CXCR2DRD1 | |
| SCHEMBL16904155 | 0.72 | KDM4E (0.43) | KDM4EHSD11B1KMT2A | |
| SCHEMBL6934553 | 0.71 | MAPT (0.43) | KDM4EKMT2ADRD2DRD3HTR1D | |
| SCHEMBL20539283 | 0.71 | DRD2 (0.44) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL7254994 | 0.71 | HSD11B1 (0.42) | HSD11B1DRD2DRD3HTR1DDRD4 | |
| SCHEMBL1560241 | 0.71 | LMNA (0.48) | KDM4EHSD11B1KMT2ACXCR2 | |
| SCHEMBL3975032 | 0.71 | HDAC4 (0.40) | KDM4EKMT2A | |
| SCHEMBL18318525 | 0.71 | KDM4E (0.35) | KDM4EKMT2ADRD2DRD3DRD4 | |
| SCHEMBL23166109 | 0.70 | EPAS1 (0.41) | KDM4EDRD2DRD3DRD4CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006451-A1 | 4-PHENYLPYRAN-2-ONE DERIVATIVES | ALMIRALL PRODESFARMA S.A. (ES) | 2003-01-23 | — | — | WO | disclosed |