Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL605278 | 0.97 | — | — | |
| SCHEMBL27608092 | 0.94 | THRB (0.42) | THRBLMNATSHRALDH1A1TDP1 | |
| SCHEMBL27698012 | 0.94 | THRB (0.42) | THRBLMNATSHRALDH1A1TDP1 | |
| SCHEMBL27682349 | 0.85 | THRB (0.40) | THRBLMNATSHR | |
| SCHEMBL5013566 | 0.84 | THRB (0.35) | THRBLMNAALDH1A1TDP1 | |
| SCHEMBL15844834 | 0.84 | — | — | |
| SCHEMBL9019108 | 0.84 | ALDH1A1 (0.42) | THRBLMNATSHRALDH1A1 | |
| SCHEMBL2499893 | 0.84 | ALDH1A1 (0.42) | THRBLMNATSHRALDH1A1 | |
| SCHEMBL69038 | 0.82 | — | — | |
| SCHEMBL2374140 | 0.82 | THRB (0.33) | THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006442-A1 | NOVEL PREPARATION PROCESS OF 1,3-OXAZOLE-2-THIOL | BAYER CROPSCIENCE AG (DE) | 2003-01-23 | — | — | WO | disclosed |