Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7255167 | 0.83 | LTB4R2 (0.44) | LTB4R2TSHRALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7258615 | 0.82 | TSHR (0.43) | LTB4R2TSHRALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7259770 | 0.76 | HRH4 (0.40) | BRAFSRPK1ABCC1 | |
| SCHEMBL7259830 | 0.74 | MAPKAPK2 (0.38) | LTB4R2TSHRALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7259827 | 0.74 | TSHR (0.44) | TSHRALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL6755014 | 0.73 | ALDH1A1 (0.44) | TSHRALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7260764 | 0.72 | ALDH1A1 (0.43) | LTB4R2TSHRALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7256009 | 0.70 | NPC1 (0.38) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL7255070 | 0.69 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL6758117 | 0.69 | HRH4 (0.48) | LTB4R2TSHRALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099812-A1 | PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 2003-12-04 | — | — | WO | disclosed |