Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258615 | 0.91 | TSHR (0.43) | LTB4R2HDAC6TSHRALDH1A1HPGD | |
| SCHEMBL7259830 | 0.89 | MAPKAPK2 (0.38) | LTB4R2HDAC6TSHRALDH1A1HPGD | |
| SCHEMBL7260764 | 0.87 | ALDH1A1 (0.43) | LTB4R2HDAC6TSHRALDH1A1HPGD | |
| SCHEMBL7259765 | 0.83 | LTB4R2 (0.39) | LTB4R2TSHRALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7259827 | 0.83 | TSHR (0.44) | TSHRALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL7255070 | 0.82 | ALDH1A1 (0.40) | HDAC6ALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL7255149 | 0.76 | NR1H4 (0.36) | ALDH1A1HPGDSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL7256248 | 0.76 | LMNA (0.40) | TSHRALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL7259783 | 0.74 | MAPKAPK2 (0.39) | SMN1; SMN2 | |
| SCHEMBL7256246 | 0.70 | LMNA (0.40) | TSHRALDH1A1HPGDSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099812-A1 | PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 2003-12-04 | — | — | WO | claimed |
| WO-2003099812-A1 | PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 2003-12-04 | — | — | WO | disclosed |