Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256446 | 0.85 | KMO (0.43) | TNF | |
| SCHEMBL20945081 | 0.69 | KAT2B (0.48) | TNF | |
| SCHEMBL216349 | 0.67 | TYR (0.43) | TNF | |
| SCHEMBL20945103 | 0.66 | TNF (0.52) | TNF | |
| SCHEMBL7256318 | 0.66 | RAB9A (0.40) | — | |
| SCHEMBL13833770 | 0.65 | MEN1 (0.54) | TNF | |
| SCHEMBL17807346 | 0.65 | TNF (0.58) | TNF | |
| SCHEMBL5165588 | 0.65 | PTGS1 (0.60) | TNF | |
| SCHEMBL5165278 | 0.65 | PTGS1 (0.60) | TNF | |
| SCHEMBL8570508 | 0.64 | CYP1A2 (0.73) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103668-A1 | PYRIDIN-2-ONE AND QUINOLIN-2-ONE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS ANTIBACTERIALS | KARO BIO AB (SE) | 2003-12-18 | — | — | WO | disclosed |