Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TNF | P01375 | 17/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13833765 | 0.87 | ALDH1A1 (0.41) | MEN1KMT2ATNF | |
| SCHEMBL13833760 | 0.86 | KAT2B (0.41) | MEN1KMT2ATNF | |
| SCHEMBL13833787 | 0.82 | KDM4E (0.43) | MEN1KMT2ACREBBP | |
| SCHEMBL13833769 | 0.81 | PDE4A (0.40) | MEN1KMT2ATNFLMNA | |
| SCHEMBL9120180 | 0.78 | PDE4A (0.48) | KMT2ATNFLMNA | |
| SCHEMBL24666581 | 0.75 | ALDH1A1 (0.48) | MEN1KMT2ALMNA | |
| SCHEMBL21695505 | 0.72 | LMNA (0.74) | KMT2ALMNACREBBP | |
| SCHEMBL11210331 | 0.72 | TNF (0.58) | TNF | |
| SCHEMBL8026931 | 0.72 | ALDH1A1 (0.51) | MEN1KMT2A | |
| SCHEMBL11210438 | 0.71 | TNF (0.52) | MEN1KMT2ATNFLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012149604-A1 | BIS-THYMINE DERIVATIVES AND PHOTO-REVERSIBLE POLYMERS THEREOF | MONASH UNIVERSITY (AU) | 2012-11-08 | — | — | WO | disclosed |