Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 4/20 | 1.00 |
| ▸ | NSD2 | O96028 | 3/20 | 1.00 |
| ▸ | HKDC1 | Q2TB90 | 3/20 | 1.00 |
| ▸ | TDP2 | O95551 | 2/20 | 1.00 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.83 |
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | RAB9A | P51151 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | GALK1 | P51570 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.71 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.71 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.47 |
| ▸ | PTPRC | P08575 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31290115 | 0.87 | APAF1 (0.77) | APAF1NSD2HKDC1TDP2DNMT1 | |
| SCHEMBL249168 | 0.87 | APAF1 (0.77) | APAF1NSD2HKDC1TDP2DNMT1 | |
| SCHEMBL31290245 | 0.85 | APAF1 (0.74) | APAF1NSD2HKDC1TDP2DNMT1 | |
| SCHEMBL4876610 | 0.85 | APAF1 (0.74) | APAF1NSD2HKDC1TDP2DNMT1 | |
| SCHEMBL30601628 | 0.83 | APAF1 (1.00) | APAF1NSD2HKDC1TDP2DNMT1 | |
| SCHEMBL4649553 | 0.83 | DNMT1 (0.83) | APAF1NSD2HKDC1TDP2DNMT1 | |
| SCHEMBL10037145 | 0.83 | DNMT1 (0.77) | APAF1NSD2HKDC1TDP2DNMT1 | |
| SCHEMBL4647391 | 0.83 | APAF1 (1.00) | APAF1NSD2HKDC1TDP2DNMT1 | |
| SCHEMBL29203715 | 0.76 | APAF1 (0.62) | APAF1NSD2HKDC1TDP2DNMT1 | |
| SCHEMBL1242685 | 0.75 | MAPT (0.67) | APAF1NSD2HKDC1TDP2DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994879-B1 | PHOTOCHROMATIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN POLYMERIC MATERIALS | GREAT LAKES CHEMICAL EUROP (CH) | 2003-09-24 | — | — | EP | disclosed |
| US-6414057-B1 | STRESS RESISTANCE, DYEABLE | GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) | 2002-07-02 | — | — | US | disclosed |
| US-5905148-A | Photochromic spirooxazine polysiloxanes | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1999-05-18 | — | — | US | disclosed |
| EP-0245020-B1 | PHOTOCHROMIC ARTICLES | PILKINGTON PLC (GB) | 1991-10-02 | — | — | EP | disclosed |
| US-4913544-A | WINDOWS, OPTICAL GLASS | PILKINGTON PLC (GB) | 1990-04-03 | — | — | US | disclosed |
| EP-0245020-A2 | Photochromic articles | PILKINGTON PLC (GB) | 1987-11-11 | — | — | EP | disclosed |