SCHEMBL7260246

SCHEMBL7260246

OCC(O)(CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7254535 0.81
SCHEMBL7641162 0.80 LMNA (0.42) THRB
SCHEMBL7643011 0.80 LMNA (0.42) THRB
SCHEMBL7254779 0.79 THRB (0.31) THRB
SCHEMBL4588079 0.78 CA2 (0.33) THRB
SCHEMBL3058414 0.77 LMNA (0.37) THRB
SCHEMBL8618375 0.76
SCHEMBL8613627 0.76
SCHEMBL8614275 0.75 LMNA (0.35) THRB
SCHEMBL17997086 0.75 LMNA (0.35) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003070714-A1 FLUOROUS ACETYLATION UNISEARCH LIMITED (AU) 2003-08-28 WO claimed
WO-2003070714-A1 FLUOROUS ACETYLATION UNISEARCH LIMITED (AU) 2003-08-28 WO disclosed