SCHEMBL726065

SCHEMBL726065

CCC(C)(C)P(Cc1ccccc1C)C(C)(C)CC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.41
KMT2A Q03164 1/20 0.38
CHRM2 P08172 1/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
MAPT P10636 1/20 0.35
ACHE P22303 2/20 0.35
TSHR P16473 1/20 0.35
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34
NPC1 O15118 1/20 0.34
GALR3 O60755 1/20 0.34
NR2F2 P24468 1/20 0.34
RAB9A P51151 1/20 0.34
DAO P14920 1/20 0.33
CYP2A13 Q16696 1/20 0.33
MGLL Q99685 1/20 0.33
HPGD P15428 2/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29703786 0.87 GABRA1 (0.36) ACHEMGLL
SCHEMBL726157 0.87 GABRA1 (0.36) ACHEMGLL
SCHEMBL3680536 0.83 TAAR1 (0.43) TAAR1KMT2ACHRM2PTGS1PTGS2
SCHEMBL1423139 0.83 TAAR1 (0.31) TAAR1
SCHEMBL30446002 0.83 TAAR1 (0.31) TAAR1
SCHEMBL1952150 0.80
SCHEMBL9511768 0.73 TAAR1 (0.50) TAAR1KMT2ACHRM2PTGS1PTGS2
SCHEMBL6055441 0.72 RIPK1 (0.46) TAAR1TSHRLMNAALDH1A1
SCHEMBL16524284 0.72 CYP1A2 (0.31)
SCHEMBL16524281 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4808401-B2 2011-11-02 JP claimed
JP-2005535695-A 2005-11-24 JP claimed
EP-1527038-A1 PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUDS Lucite International UK Limited (GB) 2005-05-04 EP claimed
WO-2004014834-A1 PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUDS LUCITE INTERNATIONAL UK LIMITED (GB) 2004-02-19 WO claimed
EP-1651587-A1 PROCESS FOR THE HYDROFORMYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS Lucite International UK Limited (GB) 2006-05-03 EP disclosed
EP-1527038-A1 PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUDS Lucite International UK Limited (GB) 2005-05-04 EP disclosed
WO-2005003070-A1 PROCESS FOR THE HYDROFORMYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS LUCITE INTERNATIONAL UK LIMITED (GB) 2005-01-13 WO disclosed
WO-2004014834-A1 PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUDS LUCITE INTERNATIONAL UK LIMITED (GB) 2004-02-19 WO disclosed