Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 7/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29703786 | 1.00 | GABRA1 (0.36) | GABRA1GABRB2RIPK1MGLLBCHE | |
| SCHEMBL726065 | 0.87 | TAAR1 (0.41) | MGLLACHE | |
| SCHEMBL1423139 | 0.82 | TAAR1 (0.31) | — | |
| SCHEMBL30446002 | 0.82 | TAAR1 (0.31) | — | |
| SCHEMBL16524284 | 0.82 | CYP1A2 (0.31) | — | |
| SCHEMBL29381329 | 0.80 | GABRA1 (0.33) | GABRA1GABRB2RIPK1MGLLBCHE | |
| SCHEMBL34189 | 0.80 | GABRA1 (0.33) | GABRA1GABRB2RIPK1MGLLBCHE | |
| SCHEMBL2145797 | 0.80 | KDM4E (0.35) | — | |
| SCHEMBL16524281 | 0.80 | — | — | |
| SCHEMBL6055441 | 0.79 | RIPK1 (0.46) | RIPK1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928061-B | Continuous process for the carbonylation of ethylene | 璐彩特国际英国有限公司 | 2020-08-28 | — | — | CN | claimed |
| EP-2794548-B1 | A CONTINUOUS PROCESS FOR THE CARBONYLATION OF ETHYLENE | LUCITE INT UK LTD (GB) | 2019-05-15 | — | — | EP | claimed |
| US-9382190-B2 | Continuous process for the carbonylation of ethylene | LUCITE INTERNATIONAL UK LIMITED (GB) | 2016-07-05 | — | — | US | claimed |
| US-20150099896-A1 | CONTINUOUS PROCESS FOR THE CARBONYLATION OF ETHYLENE | LUCITE INTERNATIONAL UK LIMITED (GB) | 2015-04-09 | — | — | US | claimed |
| EP-2794548-A1 | A CONTINUOUS PROCESS FOR THE CARBONYLATION OF ETHYLENE | Lucite International UK Limited (GB) | 2014-10-29 | — | — | EP | claimed |
| EP-2007703-B1 | METAL COMPLEXES FOR USE IN THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS | LUCITE INT UK LTD (GB) | 2013-12-18 | — | — | EP | claimed |
| WO-2013093472-A1 | A CONTINUOUS PROCESS FOR THE CARBONYLATION OF ETHYLENE | LUCITE INTERNATIONAL UK LIMITED (GB) | 2013-06-27 | — | — | WO | claimed |
| US-8445711-B2 | Metal complexes | LUCITE INTERNATIONAL UK LIMITED (GB) | 2013-05-21 | — | — | US | claimed |
| JP-4808401-B2 | — | — | 2011-11-02 | — | — | JP | claimed |
| US-20100197958-A1 | PROCESS FOR THE CARBONYLATION OF AN ETHYLENICALLY UNSATURATED COMPOUND AND A CATALYST SYSTEM | LUCITE INTERNATIONAL UK LIMITED (GB) | 2010-08-05 | — | — | US | claimed |
| WO-2007119079-A1 | METAL COMPLEXES FOR USE IN THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS | LUCITE INTERNATIONAL UK LIMITED (GB) | 2007-10-25 | — | — | WO | claimed |
| US-20060128985-A1 | Carbonylation of vinyl acetate | LUCITE INTERNATIONAL, INC. | 2006-06-15 | — | — | US | claimed |
| US-20060122435-A1 | Process for the carbonylation of ethylenically unsaturated compounds | LUCITE INTERNATIONAL UK LIMITED (GB) | 2006-06-08 | — | — | US | claimed |
| US-7026473-B2 | Process for the carbonylation of pentenenitrile | SHELL OIL COMPANY (US) | 2006-04-11 | — | — | US | claimed |
| JP-2006508162-A | — | — | 2006-03-09 | — | — | JP | claimed |
| JP-2005535695-A | — | — | 2005-11-24 | — | — | JP | claimed |
| EP-1565425-A1 | CARBONYLATION OF VINYL ACETATE | Lucite International UK Limited (GB) | 2005-08-24 | — | — | EP | claimed |
| EP-1527038-A1 | PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUDS | Lucite International UK Limited (GB) | 2005-05-04 | — | — | EP | claimed |
| WO-2004050599-A1 | CARBONYLATION OF VINYL ACETATE | LUCITE INTERNATIONAL UK LIMITED (GB) | 2004-06-17 | — | — | WO | claimed |
| WO-2004014834-A1 | PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUDS | LUCITE INTERNATIONAL UK LIMITED (GB) | 2004-02-19 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128985-A1 | Carbonylation of vinyl acetate | PCCA, LDHA, PC | GABRA1 1507/4885GABRB2 1800/4885RIPK1 3250/4885 |
| US-20150099896-A1 | CONTINUOUS PROCESS FOR THE CARBONYLATION OF ETHYLENE | SCD, ELOVL6, ALK | GABRA1 2017/4885GABRB2 2955/4885RIPK1 1724/4885 |
| US-20060122435-A1 | Process for the carbonylation of ethylenically unsaturated compounds | CYC1, CYCS, COX5A | GABRA1 2866/4885GABRB2 2928/4885RIPK1 1350/4885 |
| US-20100197958-A1 | PROCESS FOR THE CARBONYLATION OF AN ETHYLENICALLY UNSATURATED COMPOUND AND A CATALYST SYSTEM | ALOX5, ACSL5, ELOVL5 | GABRA1 2532/4885GABRB2 2809/4885RIPK1 2257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.