Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2107018 | 0.87 | SMN1; SMN2 (0.36) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7254871 | 0.87 | ALDH1A1 (0.32) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7757624 | 0.85 | SMN1; SMN2 (0.39) | KMT2AALDH1A1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL7256071 | 0.83 | ALDH1A1 (0.32) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7258815 | 0.83 | MEN1 (0.33) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL7255873 | 0.83 | ALDH1A1 (0.38) | KMT2AALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL5199239 | 0.83 | UPP1 (0.44) | — | |
| SCHEMBL7258812 | 0.83 | TK1 (0.35) | MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7255075 | 0.82 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5200101 | 0.81 | SMN1; SMN2 (0.34) | MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057677-A1 | ANTI-RETROVIRAL 5,6-DISUBSTITUTED ACYCLOPYRIMIDINE NUCLEOSIDE DERIVATIVES | SYDDANSK UNIVERSITET (DK) | 2003-07-17 | — | — | WO | disclosed |