Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119053 | 0.93 | SMN1; SMN2 (0.35) | SMN1; SMN2KMT2ALMNAALDH1A1MAPK1 | |
| SCHEMBL9119058 | 0.93 | SMN1; SMN2 (0.35) | SMN1; SMN2KMT2ALMNAALDH1A1MAPK1 | |
| SCHEMBL7756600 | 0.86 | ALDH1A1 (0.37) | SMN1; SMN2KMT2ALMNAALDH1A1MAPK1 | |
| SCHEMBL7756611 | 0.86 | ALDH1A1 (0.37) | SMN1; SMN2KMT2ALMNAALDH1A1MAPK1 | |
| SCHEMBL7756666 | 0.85 | TPH1 (0.37) | SMN1; SMN2KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL7260719 | 0.85 | MEN1 (0.35) | SMN1; SMN2KMT2ALMNAALDH1A1MAPK1 | |
| SCHEMBL7759889 | 0.85 | LMNA (0.47) | KMT2ALMNAALDH1A1KDM4EMAPT | |
| SCHEMBL7758263 | 0.82 | TP53 (0.36) | SMN1; SMN2KMT2ALMNAALDH1A1TP53 | |
| SCHEMBL7758268 | 0.82 | TP53 (0.36) | SMN1; SMN2KMT2ALMNAALDH1A1TP53 | |
| SCHEMBL2107018 | 0.80 | SMN1; SMN2 (0.36) | SMN1; SMN2KMT2AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736015-B1 | ANTIVIRAL 2,4-PYRIMIDINDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2001-03-07 | — | — | EP | disclosed |
| US-5747500-A | VIRICIDES FOR AIDS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-05-05 | — | — | US | disclosed |