Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PDK1 | Q15118 | 12/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7255144 | 0.90 | GAA (0.59) | GAATSHRPDK1ALDH1A1KDM4E | |
| SCHEMBL7259737 | 0.75 | FNTA (0.51) | — | |
| SCHEMBL7260743 | 0.75 | ALDH1A1 (0.57) | ALDH1A1KDM4ENPC1USP2MAPT | |
| SCHEMBL17212160 | 0.73 | ALDH1A1 (0.53) | ALDH1A1KDM4ENPC1USP2MAPT | |
| SCHEMBL13571398 | 0.72 | TSHR (0.84) | GAATSHRPDK1NPC1RAB9A | |
| SCHEMBL18464035 | 0.71 | KMT2A (0.57) | GAATSHRALDH1A1NPC1RAB9A | |
| SCHEMBL18464136 | 0.71 | TSHR (0.54) | GAATSHRALDH1A1KDM4ENPC1 | |
| SCHEMBL3059132 | 0.70 | ALDH1A1 (0.62) | GAAALDH1A1KDM4ERAB9ALMNA | |
| SCHEMBL6735689 | 0.69 | GRM2 (0.60) | GAATSHRPDK1ALDH1A1KDM4E | |
| SCHEMBL22289326 | 0.69 | GAA (0.73) | GAATSHRALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099812-A1 | PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 2003-12-04 | — | — | WO | disclosed |