Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 11/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 11/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6727719 | 0.81 | CA1 (0.69) | ALDH1A1LTA4HPOLB | |
| SCHEMBL17212160 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNACYP3A4CYP2C9 | |
| SCHEMBL13766317 | 0.75 | ALDH1A1 (0.73) | ALDH1A1KDM4ECYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7260731 | 0.75 | GAA (0.55) | ALDH1A1KDM4ELMNACYP3A4NPC1 | |
| SCHEMBL5440630 | 0.74 | ALDH1A1 (0.66) | ALDH1A1KDM4ELMNACYP1A2CYP2D6 | |
| SCHEMBL5735703 | 0.74 | ABL1 (0.52) | ALDH1A1KDM4ECYP2C19CYP1A2NPC1 | |
| SCHEMBL6727493 | 0.73 | TSHR (0.58) | ALDH1A1KDM4ERAB9AMAPTSMN1; SMN2 | |
| SCHEMBL2636199 | 0.73 | LTA4H (0.67) | ALDH1A1LMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2907021 | 0.73 | L3MBTL1 (0.58) | ALDH1A1KDM4ECYP3A4CYP2C19CYP1A2 | |
| SCHEMBL2907654 | 0.73 | RECQL (0.59) | ALDH1A1KDM4ECYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099812-A1 | PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 2003-12-04 | — | — | WO | disclosed |