Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 4/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7260731 | 0.90 | GAA (0.55) | GAATSHRPDK1ALDH1A1KDM4E | |
| SCHEMBL13571398 | 0.75 | TSHR (0.84) | GAATSHRLTB4R2PDK1LMNA | |
| SCHEMBL7260764 | 0.74 | ALDH1A1 (0.43) | GAATSHRLTB4R2ALDH1A1HPGD | |
| SCHEMBL7255356 | 0.73 | FNTA (0.49) | MAPKAPK2 | |
| SCHEMBL364612 | 0.72 | ALDH1A1 (0.62) | ALDH1A1HPGDCYP3A4 | |
| SCHEMBL22289326 | 0.72 | GAA (0.73) | GAATSHRALDH1A1LMNAHTT | |
| SCHEMBL7255242 | 0.70 | PDK1 (0.41) | GAAPDK1ALDH1A1KDM4ELMNA | |
| SCHEMBL8332050 | 0.69 | KMT2A (0.71) | GAATSHRLTB4R2PDK1ALDH1A1 | |
| SCHEMBL11835262 | 0.69 | GAA (0.63) | GAATSHRALDH1A1LMNAHTT | |
| SCHEMBL1399532 | 0.69 | GAA (0.56) | GAATSHRALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099812-A1 | PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 2003-12-04 | — | — | WO | claimed |
| WO-2003099812-A1 | PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 2003-12-04 | — | — | WO | disclosed |