Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421641 | 0.83 | NAAA (0.38) | PRKCAMEN1CYP2C19RECQLKMT2A | |
| SCHEMBL3577130 | 0.81 | PRKCA (0.50) | PRKCAPRKCD | |
| SCHEMBL1439932 | 0.72 | PRKCA (0.52) | PRKCAPRKCD | |
| SCHEMBL128581 | 0.72 | — | — | |
| SCHEMBL23049568 | 0.71 | PRKCA (0.51) | PRKCAMEN1KMT2APRKCD | |
| SCHEMBL9824006 | 0.71 | PRKCA (0.51) | PRKCACYP2C19PRKCD | |
| SCHEMBL7338739 | 0.70 | NAAA (0.40) | PRKCACYP2C19 | |
| SCHEMBL20237067 | 0.69 | PRKCA (0.58) | PRKCAPRKCD | |
| SCHEMBL13798817 | 0.69 | PRKCA (0.40) | PRKCAMEN1CYP2C19RECQLKMT2A | |
| SCHEMBL9001033 | 0.69 | PRKCA (0.81) | PRKCAPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552029-B1 | For therapy of rheumatoid arthritis, psoriasis, graft v. host disease, asthma, atopic dermatitis, allergic rhinitis, allergic conjunctivitis, complications following percutaneous transluminal coronary angioplasty, thrombosis | CELLTECH R&D LIMITED (GB) | 2003-04-22 | — | — | US | disclosed |