Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7260758 | 0.81 | PRKCA (0.47) | PRKCAPRKCD | |
| SCHEMBL3218918 | 0.81 | TDP1 (0.52) | PRKCATDP1TSHRCHRM2CHRM4 | |
| SCHEMBL6871769 | 0.78 | PRKCA (0.52) | PRKCATDP1TSHRGAAPRKCD | |
| SCHEMBL6882163 | 0.76 | PRKCA (0.58) | PRKCATDP1TSHR | |
| SCHEMBL1439932 | 0.75 | PRKCA (0.52) | PRKCATSHRGAAPRKCDPOLB | |
| SCHEMBL23049679 | 0.74 | PRKCA (0.50) | PRKCATDP1GAAPRKCDPOLB | |
| SCHEMBL14727840 | 0.74 | PRKCA (0.50) | PRKCATDP1GAAPRKCDPOLB | |
| SCHEMBL9001018 | 0.73 | PRKCA (0.70) | PRKCATDP1GAAPRKCDPOLB | |
| SCHEMBL2100144 | 0.73 | — | — | |
| SCHEMBL20599585 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210290787-A1 | MACROCYCLE CONJUGATES | LUMIPHORE, INC. | 2021-09-23 | — | — | US | disclosed |
| US-20120172323-A1 | METHODS FOR TREATING MALARIA, TUBERCULOSIS AND MAC DISEASES | CEMPRA PHARMACEUTICALS, INC. (US) | 2012-07-05 | — | — | US | disclosed |
| US-20100081650-A1 | Antimicrobial Compounds | AXTEN JEFFREY MICHAEL | 2010-04-01 | — | — | US | disclosed |
| EP-1560821-A4 | ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM CORP (US) | 2007-07-25 | — | — | EP | disclosed |
| EP-1560821-A2 | ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-08-10 | — | — | EP | disclosed |
| EP-1537123-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004096982-A2 | ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-11-11 | — | — | WO | disclosed |
| WO-2004002992-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-01-08 | — | — | WO | disclosed |
| EP-1214314-A2 | AMINOPIPERIDINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2002-06-19 | — | — | EP | disclosed |
| EP-1202987-A2 | QUINOLINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001007433-A2 | QUINOLINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-02-01 | — | — | WO | disclosed |
| WO-2001007432-A2 | AMINOPIPERIDINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210290787-A1 | MACROCYCLE CONJUGATES | FOLH1, KLK3, CD47 | PRKCA 3809/4885TDP1 3364/4885TSHR 3436/4885 |
| US-20120172323-A1 | METHODS FOR TREATING MALARIA, TUBERCULOSIS AND MAC DISEASES | MACO1, MPI, ITGAM | PRKCA 2942/4885TDP1 4130/4885TSHR 1736/4885 |
| US-20100081650-A1 | Antimicrobial Compounds | ELANE, NISCH, PIGS | PRKCA 4672/4885TDP1 3783/4885TSHR 4018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.