SCHEMBL7260805

SCHEMBL7260805

O=Cn1ccnc1-c1nccn1C=O

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALDH1A1 P00352 1/20 0.34
BRD4 O60885 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8464633 0.81 MAPK9 (0.41) LMNAALDH1A1
SCHEMBL2906953 0.80
SCHEMBL28279446 0.75
SCHEMBL27332692 0.75
SCHEMBL27495376 0.75
SCHEMBL548609 0.75
SCHEMBL16296076 0.75
SCHEMBL9254062 0.75
SCHEMBL27893063 0.70 ALDH1A1 (0.33) ALDH1A1
SCHEMBL4278010 0.69 CA12 (0.40) LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003104237-A1 2,7,12,17 ALKENYL, ARYL AND HETEROARYL DERIVED FROM 3,6,13,16-TETRAAZAPORPHYCENE, METHOD, INTERMEDIATE COMPOUND AND CORRESPONDING UTILIZATIONS INSTITUT QUIMIC DE SARRIA CETS (ES) 2003-12-18 WO disclosed