SCHEMBL7260846

SCHEMBL7260846

C=CCOCCOC(=O)OCCOCC=C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.48
TSHR P16473 7/20 0.48
TP53 P04637 2/20 0.48
HIF1A Q16665 2/20 0.48
HSD17B10 Q99714 2/20 0.48
TDP1 Q9NUW8 2/20 0.39
POLB P06746 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP3A4 P08684 2/20 0.36
THRB P10828 2/20 0.36
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA7 P43166 1/20 0.34
MAPT P10636 1/20 0.34
CACNA1B Q00975 1/20 0.34
APBA1 Q02410 1/20 0.34
CA9 Q16790 1/20 0.31
PKM P14618 1/20 0.31
CTDSP1 Q9GZU7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10902737 0.98 TSHR (0.52) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL5860449 0.98 TSHR (0.52) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL7265581 0.98 TSHR (0.52) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL8780696 0.94 TSHR (0.48) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL22204348 0.91 TSHR (0.45) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL14456442 0.90 ALDH1A1 (0.50) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL7260881 0.90 TSHR (0.41) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL10870570 0.88 TSHR (0.52) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL10886350 0.88 TSHR (0.52) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL9714112 0.88 TSHR (0.52) ALDH1A1TSHRTP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4594288-A Optical lenses having a scratch-resistant coating ESSILOR INTERNATIONAL (FR) 1986-06-10 US claimed
EP-0787749-B1 NOVEL ALLYL ETHERS, POLYMERS AND POLYMERIC SOLID ELECTROLYTES MITSUI CHEMICALS INC (JP) 2003-04-02 EP disclosed
US-5977277-A Acrylic ester, novel allyl ether, novel allyl carbonate, acrylic ester polymer, allyl ether polymer, allyl carbonate polymer and polymeric solid electrolyte MITSUI PETROCHEMICAL INDUSTRIES, LTD (JP) 1999-11-02 US disclosed
EP-0787749-A1 NOVEL ACRYLATES, NOVEL ALLYL ETHERS, NOVEL ALLYL CARBONATES, ACRYLATE POLYMERS, ALLYL ETHER POLYMERS, ALLYL CARBONATE POLYMERS, AND SOLID POLYELECTROLYTES MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-08-06 EP disclosed
EP-0338544-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-10-25 EP disclosed
US-4594288-A Optical lenses having a scratch-resistant coating ESSILOR INTERNATIONAL (FR) 1986-06-10 US disclosed