SCHEMBL7260889

SCHEMBL7260889

Brc1cnc(-c2ncc(Br)c3ccccc23)c2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 2/20 0.50
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
ALDH1A1 P00352 3/20 0.38
MAPT P10636 2/20 0.38
HTT P42858 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HPGD P15428 2/20 0.38
PRNP P04156 1/20 0.38
KDM4E B2RXH2 3/20 0.33
CYP1A2 P05177 2/20 0.33
GPR3 P46089 2/20 0.33
AXL P30530 2/20 0.33
IGF1R P08069 1/20 0.33
CYP2C19 P33261 1/20 0.32
GRM4 Q14833 1/20 0.32
APAF1 O14727 1/20 0.31
TDP2 O95551 1/20 0.31
CASP3 P42574 1/20 0.31
SENP8 Q96LD8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10782921 0.87 ADORA2A (0.47) PLAUALDH1A1MAPTHTTSMN1; SMN2
SCHEMBL11976492 0.80 ALDH1A1 (0.47) PLAUMEN1KMT2AALDH1A1MAPT
SCHEMBL1446736 0.80 PLAU (0.50) PLAUMEN1KMT2AALDH1A1MAPT
SCHEMBL29751039 0.80 PLAU (0.50) PLAUMEN1KMT2AALDH1A1MAPT
SCHEMBL13945549 0.78 PLAU (0.48) PLAUMEN1KMT2AALDH1A1MAPT
SCHEMBL6970878 0.78 CRHR1 (0.45) PLAUMEN1KMT2AALDH1A1MAPT
SCHEMBL11976491 0.76 KDM4E (0.43) PLAUKMT2AALDH1A1SMN1; SMN2KDM4E
SCHEMBL1445945 0.76 PLAU (0.52) PLAUMEN1KMT2AALDH1A1MAPT
SCHEMBL1396177 0.76 PLAU (0.47) PLAUMEN1KMT2AALDH1A1MAPT
SCHEMBL2345378 0.76 PLAU (0.47) PLAUMEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1006135-B1 Conjugated N-fluoropyridinium salt-containing polymer and use of the same DAIKIN IND LTD (JP) 2003-02-12 EP disclosed
EP-0787719-B1 CONJUGATED N-FLUOROPYRIDINIUM SALT POLYMER AND USE THEREOF DAIKIN IND LTD (JP) 2001-08-16 EP disclosed
EP-1006135-A1 Conjugated N-fluoropyridinium salt-containing polymer and use of the same DAIKIN INDUSTRIES, LIMITED (JP) 2000-06-07 EP disclosed
US-5736274-A ANODE ACTIVE MATERIAL AND SOLID ELECTROLYTE FOR BATTERIES; HIGH ELECTROMOTIVE FORCE; HIGH ENERGY DENSITY; POLLUTION CONTROL; FLUORINATING AGENTS; LOW INTERNAL RESISTANCE IN CHARGING AND DISCHARGING DAIKIN INDUSTRIES, LTD. (JP) 1998-04-07 US disclosed
EP-0787719-A1 CONJUGATED N-FLUOROPYRIDINIUM SALT POLYMER AND USE THEREOF DAIKIN INDUSTRIES, LTD. (JP) 1997-08-06 EP disclosed