Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 4/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.70 |
| ▸ | HTR2A | P28223 | 2/20 | 0.61 |
| ▸ | HTR7 | P34969 | 2/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | HTR6 | P50406 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7259962 | 0.99 | ADRA1D (0.72) | ADRA1DSLC6A4HTR2AHTR7DRD2 | |
| Hydrochloric Acid SCHEMBL7256791 | 0.99 | ADRA1D (0.72) | ADRA1DSLC6A4HTR2AHTR7DRD2 | |
| SCHEMBL5730515 | 0.99 | ADRA1D (0.69) | ADRA1DSLC6A4HTR2AHTR7HTR1A | |
| Hydrochloric Acid SCHEMBL7261121 | 0.98 | ADRA1D (0.70) | ADRA1DSLC6A4HTR2AHTR7HTR1A | |
| SCHEMBL6133590 | 0.97 | ADRA1D (0.71) | ADRA1DSLC6A4HTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL7259035 | 0.96 | ADRA1D (0.71) | ADRA1DSLC6A4HTR2AHTR7 | |
| SCHEMBL9671736 | 0.92 | HTR7 (0.67) | ADRA1DSLC6A4HTR2AHTR7HTR1A | |
| Hydrochloric Acid SCHEMBL7261098 | 0.91 | HTR7 (0.66) | ADRA1DSLC6A4HTR2AHTR7HTR1A | |
| SCHEMBL5705223 | 0.88 | CYP1A2 (0.56) | ADRA1DSLC6A4HTR2AHTR7HTR1A | |
| SCHEMBL7260967 | 0.86 | ADRA1D (0.67) | ADRA1DSLC6A4HTR2AHTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642228-B1 | Treating ocular tension, carcinoma, sarcoma, tumentia, circulatory disease, or hypertension | TORAY INDUSTRIES, INC. (JP) | 2003-11-04 | — | — | US | disclosed |
| EP-1106605-A1 | ALPHA1B-ADRENERGIC RECEPTOR ANTAGONISTS | TORAY INDUSTRIES, INC. (JP) | 2001-06-13 | — | — | EP | disclosed |