Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 3/20 | 0.67 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.64 |
| ▸ | DRD2 | P14416 | 6/20 | 0.64 |
| ▸ | HTR1A | P08908 | 6/20 | 0.62 |
| ▸ | HTR7 | P34969 | 5/20 | 0.62 |
| ▸ | HTR6 | P50406 | 5/20 | 0.62 |
| ▸ | HTR2A | P28223 | 4/20 | 0.62 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7255426 | 0.99 | ADRA1D (0.68) | ADRA1DADRA1BSLC6A4DRD2HTR1A | |
| SCHEMBL5730515 | 0.87 | ADRA1D (0.69) | ADRA1DSLC6A4DRD2HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL7261121 | 0.86 | ADRA1D (0.70) | ADRA1DSLC6A4DRD2HTR1AHTR7 | |
| SCHEMBL7260935 | 0.86 | ADRA1D (0.71) | ADRA1DSLC6A4DRD2HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL7256791 | 0.85 | ADRA1D (0.72) | ADRA1DSLC6A4DRD2HTR7HTR2A | |
| Hydrochloric Acid SCHEMBL7259962 | 0.85 | ADRA1D (0.72) | ADRA1DSLC6A4DRD2HTR7HTR2A | |
| SCHEMBL9034357 | 0.85 | DRD2 (0.60) | ADRA1DADRA1BSLC6A4DRD2HTR1A | |
| SCHEMBL6133590 | 0.85 | ADRA1D (0.71) | ADRA1DSLC6A4HTR7HTR2A | |
| Hydrochloric Acid SCHEMBL7259035 | 0.84 | ADRA1D (0.71) | ADRA1DSLC6A4HTR7HTR2A | |
| Hydrochloric Acid SCHEMBL7260113 | 0.82 | ADRA1D (0.83) | ADRA1DADRA1BSLC6A4DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642228-B1 | Treating ocular tension, carcinoma, sarcoma, tumentia, circulatory disease, or hypertension | TORAY INDUSTRIES, INC. (JP) | 2003-11-04 | — | — | US | disclosed |
| EP-1106605-A1 | ALPHA1B-ADRENERGIC RECEPTOR ANTAGONISTS | TORAY INDUSTRIES, INC. (JP) | 2001-06-13 | — | — | EP | disclosed |