Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 4/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.65 |
| ▸ | CCR2 | P41597 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7255564 | 0.95 | ADRA1D (0.67) | ADRA1DSLC6A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL7259921 | 0.85 | ADRA1D (0.70) | ADRA1DSLC6A4 | |
| Hydrochloric Acid SCHEMBL7259016 | 0.85 | ADRA1D (0.56) | ADRA1DSLC6A4CYP2D6 | |
| SCHEMBL7260934 | 0.82 | ADRA1D (1.00) | ADRA1DSLC6A4 | |
| Hydrochloric Acid SCHEMBL7255629 | 0.81 | OPRM1 (0.62) | ADRA1DSLC6A4 | |
| Hydrochloric Acid SCHEMBL7823791 | 0.81 | ADRA1D (0.70) | ADRA1DSLC6A4 | |
| Hydrochloric Acid SCHEMBL7259920 | 0.80 | ADRA1D (0.97) | ADRA1DSLC6A4 | |
| Hydrochloric Acid SCHEMBL7259157 | 0.80 | ADRA1D (0.90) | ADRA1DSLC6A4CYP2D6 | |
| SCHEMBL5705177 | 0.79 | SLC6A4 (1.00) | ADRA1DSLC6A4CYP2D6 | |
| SCHEMBL5705183 | 0.79 | SLC6A4 (1.00) | ADRA1DSLC6A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642228-B1 | Treating ocular tension, carcinoma, sarcoma, tumentia, circulatory disease, or hypertension | TORAY INDUSTRIES, INC. (JP) | 2003-11-04 | — | — | US | disclosed |
| EP-1106605-A1 | ALPHA1B-ADRENERGIC RECEPTOR ANTAGONISTS | TORAY INDUSTRIES, INC. (JP) | 2001-06-13 | — | — | EP | disclosed |